Adjuvant therapy in assisted fertilization procedures

Introduction. Despite continuous advances in assisted reproductive technologies (ART), their outcomes are limited. Before introducing adjuvant therapy to improve the vitro fertilization (IVF) outcome, it is important identify appropriate groups of patients, and avoid equal approach for everyone. The objective this paper was review available literature on most commonly used aiming outcome IVF. guidelines European Society Human Reproduction Embryology American Reproductive Medicine were used, analyzed by searching Medline ? PubMed Cochrane databases using keywords each entity. Discussion. A found no consistent evidence standard use metformin patients with polycystic ovarian syndrome, nor dehydroepiandrosterone, testosterone, growth hormone premature failure or those poor response stimulation. usage prednisone aspirin general population ART also not recommended. Recently, significance oxidative stress has been emphasized, which why antioxidants form supplementation (melatonin, vitamins C, A, E, coenzyme Q) might be improving outcomes. Conclusion. modern problem infertility become strictly individual. application order procedures requires an analytical critical individual case.